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Time Completed: 01:07:02

Final Score 54%

98
82

Questions

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Microbiology

Pathogens

Question 153 of 180

Regarding Neisseria species which of the following statements is CORRECT:

Answer:

Neisseria spp. are Gram-negative diplococci. N. meningitidis is often found in the nasopharynx and respiratory flora but N. gonorrhoeae is not part of the normal flora.

Neisseria Spp.

Neisseria Meningitidis

Microorganism Neisseria Meningitidis
Gram stain Gram negative
Shape Cocci (diplococci)
Oxygen requirements Obligate aerobe
Additional features Encapsulated, Ferments glucose and maltose
Reservoir Nasopharynx
Transmission Direct contact or respiratory droplet
Diseases Meningitis and meningococcal sepsis (notifiable diseases)
Risk factors Smoking, winter, complement deficiencies (C5 - C9)

Neisseria Gonorrhoeae

Microorganism Neisseria Gonorrhoeae
Gram stain Gram negative
Shape Cocci (diplococci)
Oxygen requirements Obligate aerobe
Additional features Only ferments glucose
Transmission Sexual and peripartum
Diseases Urethritis, epididymo-orchitis, UTI, PID, septic arthritis, endocarditis, neonatal conjunctivitis

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  • Biochemistry
  • Blood Gases
  • Haematology
Biochemistry Normal Value
Sodium 135 – 145 mmol/l
Potassium 3.0 – 4.5 mmol/l
Urea 2.5 – 7.5 mmol/l
Glucose 3.5 – 5.0 mmol/l
Creatinine 35 – 135 μmol/l
Alanine Aminotransferase (ALT) 5 – 35 U/l
Gamma-glutamyl Transferase (GGT) < 65 U/l
Alkaline Phosphatase (ALP) 30 – 135 U/l
Aspartate Aminotransferase (AST) < 40 U/l
Total Protein 60 – 80 g/l
Albumin 35 – 50 g/l
Globulin 2.4 – 3.5 g/dl
Amylase < 70 U/l
Total Bilirubin 3 – 17 μmol/l
Calcium 2.1 – 2.5 mmol/l
Chloride 95 – 105 mmol/l
Phosphate 0.8 – 1.4 mmol/l
Haematology Normal Value
Haemoglobin 11.5 – 16.6 g/dl
White Blood Cells 4.0 – 11.0 x 109/l
Platelets 150 – 450 x 109/l
MCV 80 – 96 fl
MCHC 32 – 36 g/dl
Neutrophils 2.0 – 7.5 x 109/l
Lymphocytes 1.5 – 4.0 x 109/l
Monocytes 0.3 – 1.0 x 109/l
Eosinophils 0.1 – 0.5 x 109/l
Basophils < 0.2 x 109/l
Reticulocytes < 2%
Haematocrit 0.35 – 0.49
Red Cell Distribution Width 11 – 15%
Blood Gases Normal Value
pH 7.35 – 7.45
pO2 11 – 14 kPa
pCO2 4.5 – 6.0 kPa
Base Excess -2 – +2 mmol/l
Bicarbonate 24 – 30 mmol/l
Lactate < 2 mmol/l

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