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  • x

    Cutaneous Innervation of the Upper Limb

    You are asked to review a 62 year old woman who presents with a numb left arm. On examination you note she lacks sensation to the skin over

    >
  • x

    Function of Gastric Chief Cells

    Gastric chief cells secrete which of the following:

    >
  • x

    Factors affecting the Starling Curve

    If the ejection fraction increases, there will be a decrease in:

    >
  • x

    Factors affecting Lung Compliance

    Regarding compliance, which of the following statements is CORRECT:

    >
  • x

    Pharmacological Management of DKA

    Regarding the management of diabetic ketoacidosis (DKA), insulin should initially be given:

    >
  • Function of the Median Nerve

    You are reviewing a 38 year old woman who presents to the Emergency Department following a supracondylar fracture. You are concerned she ma

    >
  • x

    Innervation of the Supraspinatus Muscle

    A 72 year old retired engineer presents to the Emergency Department complaining of pain and weakness in his left shoulder. On examination yo

    >
  • Mannitol: Mechanism of Action

    What is the mechanism of action of mannitol:

    >
  • Function of the Posterior Leg Muscles

    The muscles of the posterior compartment of the leg collectively act together to primarily produce which of the following movements:

    >
  • Coagulation Cascade

    Regarding the coagulation cascade, the extrinsic pathway is primarily activated by which of the following:

    >
  • Clinical Features of Primary Adrenal Insufficiency

    A 58 year old woman with known autoimmune hypothyroidism presents to ED with flu-like symptoms and circulatory collapse. She reported weight

    >
  • Phagocytes

    Which of the following best describes the process of opsonisation:

    >
  • Clinical Features of Typhoid Fever

    A patient who has recently returned from travelling to South America, presents to ED with a fever and a 'rose spot' rash shown below. He has

    >
  • x

    Innervation of the Anterior Leg Muscles

    The muscles in the anterior compartment of the leg are all innervated by which of the following nerves:

    >
  • Parts of the Common Bile Duct

    The infraduodenal region of the common bile duct:

    >
  • x

    Theophylline: Mechanism of Action

    What is the mechanism of action of theophylline:

    >
  • Nerves of the Lumbar Plexus

    The iliohypogastric nerve supplies skin over which of the following regions:

    >
  • Pathway of the Pupillary Light Reflex

    A 49 year old man presents to ED complaining of visual disturbance in his right eye. On examination you note when you shine a light in his r

    >
  • x

    Function of Calcitonin

    Which of the following is a primary action of calcitonin:

    >
  • Clinical Features of Bronchiolitis

    A 9 month old baby is brought into the ED with a one day history of wheezing and dyspnoea. She is having difficulty feeding due to her breat

    >
  • x

    Disadvantages of Case-Control Studies

    Which of the following limitations is NOT a disadvantage of a case-control study used to identify past exposure to a risk factor in patients

    >
  • Pathway of the Gag Reflex

    Which of the following nerves is the afferent pathway of the gag reflex:

    >
  • Lobes of the Lung

    The horizontal fissure of the lung separates which of the following:

    >
  • x

    Layers of the Sole of the Foot

    The tendons of the tibialis posterior and fibularis longus muscles lie within which of the muscular layers of the sole of the foot:

    >
  • x

    Ciprofloxacin: Pharmacology

    Regarding ciprofloxacin, which of the following statements is CORRECT:

    >
  • x

    Articulations of the Sternoclavicular Joint

    You are asked to review a 76 year old man who presents with pain and tenderness over the right sternoclavicular joint. You note the sternocl

    >
  • Organelles of Eukaryotic Cells

    Regarding the human cell, which of the following cell organelles is responsible for digestion of defective proteins:

    >
  • Surface Anatomy of the Lung Root

    The hila of the lungs are located at the level of which of the following costal cartilages:

    >
  • Ascending Tracts of the Spinal Cord

    Transection of the anterolateral tract of the spinal cord results in which of the following clinical features:

    >
  • x

    Mechanism of Fat Digestion

    Regarding fat digestion, which of the following statements is CORRECT:

    >
  • Dexamethasone: Indications

    Dexamethasone would be most useful for which of the following conditions:

    >
  • Diffusing Capacity of the Lungs

    The diffusing capacity of the lungs for carbon monoxide (DLCO) may be decreased in all of the following EXCEPT for:

    >
  • Blood Supply of the Heart

    Which of the following best describes the territory of supply of the posterior interventricular artery:

    >
  • JVP Waveforms during the Cardiac Cycle

    Which of the following JVP waveforms corresponds with atrial systole:

    >
  • x

    Clinical Features of Mumps

    Regarding mumps, which of the following statements is INCORRECT:

    >
  • Platelets

    What is the approximate lifespan of the platelet:

    >
  • Ligaments of the Sternoclavicular Joint

    A 16 year old hockey player presents to the ED after colliding with another player during training. She is tender over the right clavicle an

    >
  • x

    Bursa of the Knee Joint

    Which of the following knee bursae typically communicates with the synovial cavity of the knee joint:

    >
  • Blood Supply of the Heart

    Which of the following best describes the territory of supply of the right marginal artery:

    >
  • x

    Immune Response

    Which of the following is NOT a granulocyte:

    >
  • Muscles divided during Thoracotomy

    A 29 year old is brought into ED with a penetrating stab wound to the chest. During the primary survey the patient arrests. He has no pulse.

    >
  • x

    Clinical Features of Primary Hyperthyroidism

    Which of the following biochemical patterns is most typical of primary hyperthyroidism:

    >
  • x

    Function of the Axillary Nerve

    You have been asked to review a gentleman who has sustained a fracture to the surgical neck of the humerus. You are concerned about an axill

    >
  • Renal Handling of Sodium

    Which of the following hormones' primary action is to enhance Na+ reabsorption in the distal nephron:

    >
  • Structure of the Pelvis

    The pelvic bone is formed by which of the following:

    >
  • Function of the Quadratus Lumborum Muscle

    The quadratus lumborum muscle contributes to which of the following movements:

    >
  • Control of Exocrine Pancreas Secretion

    Pancreatic exocrine secretion is increased by which of the following:

    >
  • Definition of Dalton's Law

    Which of the following states that the total pressure exerted by a mixture of gases is equal to the sum of the partial pressures of each of

    >
  • x

    Clinical Effects of Rotator Cuff Injury

    A patient presents to ED having injured his right shoulder playing basketball. You establish he has torn the most commonly injured rotator c

    >
  • Clinical Effects of Ulnar Nerve Injury

    A 24 year old butcher has sustained a deep laceration to the distal crease of the wrist where he has cut through the ulnar nerve. Which of t

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  • x

    Action Potential of the Ventricular Myocyte

    In the ventricular myocyte action potential, depolarisation occurs through the opening of:

    >
  • x

    Factors affecting the Starling Curve

    Preload is primarily dependent on the:

    >
  • x

    Anatomical Relations of the Duodenum

    A 65 year old man presents to ED complaining of abdominal pain and weight loss. Imaging shows a tumour anterior to the inferior vena cava. W

    >
  • x

    Types of Pathogen

    Which of the following organisms is an obligate pathogen:

    >
  • Clinical Effects of Oculomotor Nerve Lesion

    A 68 year old woman, with a known brain tumour, presents to ED. Her left eye is directed outwards and downwards, she is unable to open her e

    >
  • x

    Tissue Regeneration and Repair

    Which of the following is an example of a permanent cell:

    >
  • Function of the Hypoglossal Nerve

    The hypoglossal nerve innervates all of the following muscles EXCEPT for the:

    >
  • Blood Supply of the Heart

    The coronary arteries arise from which of the following:

    >
  • Transport across a Cell Membrane

    Which of the following is characterised by passive carrier-mediated transport down a chemical concentration gradient across a cell membrane:

    >
  • Cortical Areas of the Frontal Lobe

    The primary motor cortex is located in which of the following regions:

    >
  • x

    Flecainide: Mechanism of Action

    A patient presents with symptomatic fast atrial fibrillation. Your consultant decides to use flecainide. What is the main mechanism of actio

    >
  • x

    Calculation of Relative Risk Reduction

    Regarding the interpretation of risk of an outcome event when comparing a treatment and control group, how is the relative risk reduction ca

    >
  • Definition of the Osmolal Gap

    Regarding the osmolal gap, which of the following statements is CORRECT:

    >
  • x

    Clinical Features of Bronchiolitis

    Regarding bronchiolitis, which of the following statements is CORRECT:

    >
  • Typical vs Atypical Ribs

    Which of the following atypical ribs articulates with both its corresponding vertebra and the vertebra above:

    >
  • Blood Supply of the Heart

    The right atrium is primarily supplied by which of the following coronary vessels:

    >
  • Control of Gastric Acid Secretion

    Secretion of hydrochloric acid from parietal cells is inhibited by all of the following hormones EXCEPT for:

    >
  • x

    Surfaces of the Heart

    The anterior surface of the heart is formed predominantly by which of the following:

    >
  • Complications of Mumps

    Which of the following is NOT a typical complication associated with mumps:

    >
  • Heart Sounds during the Cardiac Cycle

    What does the first heart sound correspond to on the ECG waveform:

    >
  • x

    Clinical Features of Diabetes Insipidus

    Which of the following is NOT a typical clinical feature in diabetes insipidus:

    >
  • Transmission of Streptococcus Pyogenes

    Streptococcus pyogenes is transmitted via which route:

    >
  • x

    Ciprofloxacin: Drug Interactions

    Regarding drug interactions with ciprofloxacin, which of the following statements is INCORRECT:

    >
  • Clinical Features of Measles

    A 8 year old unvaccinated girl, originally from Hungary, is brought to ED by her parents who are concerned about a non-itchy rash. She has

    >
  • Anatomical Relations at the Thoracic Inlet

    Regarding the thoracic inlet, which of the following statements is CORRECT:

    >
  • Characteristics of Staphylococcus Epidermidis

    Regarding Staphylococcus epidermidis, which of the following statements is CORRECT:

    >
  • Generation of an Action Potential

    Regarding the refractory period, which of the following statements is INCORRECT:

    >
  • x

    Heparin: Side Effects

    Regarding heparin-induced thrombocytopaenia (HIT), which of the following statements is CORRECT:

    >
  • Non-Pharmacological Management of Dyspepsia/GORD

    Which of the following lifestyle changes is not likely to improve symptoms of dyspepsia/gastro-oesophageal reflux disease (GORD):

    >
  • x

    Tetracyclines: Side Effects

    Which of the following is NOT a side effect typically associated with tetracycline antibiotics:

    >
  • Paracetamol: Pharmacology

    Regarding paracetamol, which of the following statements is CORRECT:

    >
  • x

    Warfarin: Mechanism of Action

    What is the mechanism of action of warfarin:

    >
  • x

    Viruses of Herpesviridae Family

    Which of the following viruses is NOT part of the herpes family:

    >
  • Coagulation Cascade

    Regarding the coagulation cascade, the common pathway requires which of the following clotting factors:

    >
  • Function of Saliva

    Which of the following immunoglobulins is predominant in saliva:

    >
  • Microbial Mechanisms of Immune Evasion

    Which of the following microbes expresses protein A:

    >
  • x

    Muscles of the Thenar Eminence

    You have been asked to review a 32 year old pastry chef. She sustained a laceration to her left thenar eminence whilst working. Which of th

    >
  • Management of Clostridium Difficile Colitis

    A patient is sent to ED by his GP with profuse watery diarrhoea. A stool sample taken by the GP has demonstrated C. difficile cytotoxin. Fir

    >
  • Function of the Pituitary Gland

    You are reviewing a patient with known hypopituitarism. Which of the following hormones is secreted by the posterior pituitary gland:

    >
  • Anatomy of the Anterior Forearm Veins

    You have been asked to give a tutorial to a group of nurses regarding venous cannulation. As part of the session you cover the basic anatomy

    >
  • x

    Contents of the Rectus Sheath

    A patient presents with a superficial stab wound to the rectus sheath. Which of the following muscles is contained within the rectus sheath:

    >
  • x

    Factors affecting Lung Compliance

    Compliance is greater in all of the following EXCEPT for:

    >
  • Infectious Disease caused by Clostridium Perfringens

    Clostridium perfringens primarily causes which of the following infectious diseases:

    >
  • x

    Innervation of the Ovary

    The ovarian visceral afferent fibres usual follow sympathetic efferents to spinal cord segments:

    >
  • x

    Neutrophils

    What is the approximate lifespan of the circulating neutrophil:

    >
  • x

    Factors affecting Lung Compliance

    Compliance is decreased by all of the following EXCEPT for:

    >
  • Central vs Peripheral Chemoreceptors

    Ventilation may be increased by:

    >
  • Normal Partial Pressure of Nitrogen

    If the atmospheric pressure is 101 kPa, what is the partial pressure of nitrogen in dry inhaled air:

    >
  • Management of Atrial Fibrillation

    A 70 year old man is brought to ED by ambulance with sudden onset chest pain, palpitations and shortness of breath. His HR is 160 bpm and BP

    >
  • x

    Clinical Features of Diabetes Insipidus

    Which of the following biochemical patterns would be most typical of diabetes insipidus:

    >
  • x

    Theophylline: Drug Interactions

    Which of the following drugs decreases plasma-theophylline levels:

    >
  • x

    Renal Handling of Calcium

    Regarding calcium, which of the following statements is CORRECT:

    >
  • x

    Function of the Adductor Muscles

    A 32 year old builder is brought to the ED after falling through a glass sky light onto the floor below. A primary survey has been performed

    >
  • x

    Autoregulation of Renal Blood Flow

    In tubuloglomerular feedback, where is increased tubular flow rate detected in the nephron:

    >
  • x

    Anatomy of the Infraclavicular Lymph Nodes

    A 32 year old man presents to the ED with a 4 day history of fever and malaise. He has recently moved to the UK from South Africa to study.

    >
  • Regulation of Antidiuretic Hormone

    Which of the following acts to inhibit antidiuretic hormone (ADH) release from the posterior pituitary:

    >
  • x

    Clinical Effects of Femoral Nerve Injury

    A 54 year old man presents to ED complaining of leg weakness. Your colleague has examined the patient and suspects femoral nerve palsy. Whic

    >
  • Anatomical Relations of the Prostate

    Which of the following best describes the relationship of the bladder and prostate gland:

    >
  • Central vs Peripheral Chemoreceptors

    Regarding chemical control of respiration, which of the following statements is INCORRECT:

    >
  • x

    Pathophysiology of Osteomalacia

    Regarding osteomalacia, which of the following statements is CORRECT:

    >
  • x

    Cutaneous Innervation of the Lower Limb

    A 65 year old man presents to the ED complaining of loss of sensation over the lateral thigh. This area is primarily supplied by which of th

    >
  • Function of Bile

    Which of the following is NOT a function of bile:

    >
  • Inotropic Effects on the Heart

    Digoxin exhibits its positive inotropic effect by which of the following mechanisms:

    >
  • x

    Codeine: Pharmacology

    Regarding codeine, which of the following statements is INCORRECT:

    >
  • Pharmacological Management of Status Epilepticus

    Regarding the management of status epilepticus, which of the following statements is INCORRECT:

    >
  • x

    Immune Response

    Regarding Class I major histocompatibility complex (MHC) molecules, which of the following statements is INCORRECT:

    >
  • Innervation of the Pectoralis Minor Muscle

    An 18 year old man presents to the Emergency Department following a rugby match. He is complaining of pain over his left shoulder and is una

    >
  • Function of the Endothelium

    Regarding endothelin-1, which of the following statements is INCORRECT:

    >
  • Cutaneous Innervation of the Face

    The skin over the tip of the nose is primarily supplied by which of the following nerves:

    >
  • x

    Structure of the Parasympathetic Nervous System

    Parasympathetic preganglionic neurons run in which of the following cranial nerves:

    >
  • x

    ACE Inhibitors: Side Effects

    Which of the following is NOT a typical side effect of captopril:

    >
  • Function of the Loop of Henle

    In which part of the loop of Henle is water reabsorbed:

    >
  • x

    Organisation of Skeletal Muscle

    The connective tissue surrounding the whole skeletal muscle is called:

    >
  • ACE Inhibitors: Side Effects

    A patient who is taking ramipril for high blood pressure complains of a dry persistent cough. What is the mechanism of cough in ACE inhibito

    >
  • Conduction System of the Heart

    A 42 year old man presents to ED complaining of feeling light-headed. At triage, his heart rate is found to be 40-60 bpm regular rhythm. ECG

    >
  • x

    Innervation of the Gluteus Medius Muscles

    You are performing a thorough neurological examination of a 67 year old female patient. You note marked wasting of the left hip and thigh mu

    >
  • x

    Haemopoiesis

    Haemopoiesis occurs normally in all of the following organs EXCEPT:

    >
  • x

    Production of Gastrin

    Secretion of which of the following substances is inhibited by low pH:

    >
  • x

    Anatomy of the Eyeball

    Regarding the eyeball, which of the following statements is CORRECT:

    >
  • x

    Palpation of the Dorsalis Pedis Artery

    You are demonstrating a vascular examination to  group of medical students. The dorsalis pedis artery pulse is best palpated at which of t

    >
  • Dermatomal Supply of the Thoracic Wall

    The T4 dermatome is best tested at which of the following landmarks:

    >
  • Antihistamines: Side Effects

    Which of the following is NOT a common side effect of antihistamines:

    >
  • x

    Recruitment of Motor Units

    Regarding skeletal muscle contraction, which of the following statements is CORRECT:

    >
  • Acute Lymphoblastic Leukaemia

    A 4 year old boy presents to his GP with a persistent sore throat and malaise. Examination reveals bruising and splenomegaly. A full blood c

    >
  • Calculation of Interquartile Range

    What is the interquartile range of the following data set: 5, 10, 15, 20, 25, 30, 35, 40, 45, 50, 60, 70

    >
  • x

    Blood Supply of the Ovary

    The ovaries are supplied by the ovarian arteries, branches of which of the following:

    >
  • Flow through a Tube

    Which of the following does NOT affect the rate of flow of a liquid through a tube:

    >
  • x

    Control of Gastric Emptying

    Gastric emptying is increased by all of the following EXCEPT for:

    >
  • x

    Macrophages

    Which of the following specialised macrophages is NOT paired correctly with its site in the body:

    >
  • x

    Types of Data

    Which of the following is an example of discrete data:

    >
  • x

    Changes in Alveolar Pressure

    Regarding pressures and airflow during the normal breathing cycle, which of the following statements is INCORRECT:

    >
  • Definition of Virulence

    Which of the following best describes virulence:

    >
  • Clinical Features of Genital Herpes

    A 25 year old patient presents to ED complaining of painful ulcerations on her vulva. She has felt a little flu-like over the past few days

    >
  • Anatomy of the Olfactory Nerve

    Regarding the olfactory nerve, which of the following statements is CORRECT:

    >
  • Production of Somatostatin

    Somatostatin is released from which of the following cells:

    >
  • Metoclopramide: Side Effects

    Which of the following is a well recognised adverse effect of metoclopramide:

    >
  • x

    Local Control of Blood Flow

    Regarding autoregulation of local blood flow, which of the following statements is CORRECT:

    >
  • x

    Anatomy of the Eyeball

    Regarding the eyeball, which of the following statements is INCORRECT:

    >
  • x

    Interpretation of Box and Whisker Plots

    Box and whisker plots are typically used to display:

    >
  • x

    Warfarin: Pharmacology

    Regarding warfarin therapy, which of the following statements is CORRECT:

    >
  • Innervation of the Peritoneum

    Irritation of the central part of the diaphragmatic peritoneum is typically referred to:

    >
  • x

    Lesions of the Visual Pathway

    Which of the following is most likely to cause a bitemporal hemianopia:

    >
  • x

    Characteristics of Neisseria Spp.

    Regarding Neisseria species which of the following statements is CORRECT:

    >
  • x

    Calculation of Confidence Intervals for Sample Mean

    Regarding confidence intervals for the sample mean, which of the following statements is CORRECT:

    >
  • x

    Function of the Orbital Muscles

    The lateral rectus muscle acts to produce which of the following eyeball movements:

    >
  • Coagulation Cascade

    Regarding the coagulation cascade, the extrinsic pathway requires which of the following clotting factors:

    >
  • x

    Renal Handling of Phosphate

    All of the following increase renal phosphate excretion EXCEPT for:

    >
  • Heparin: Reversal Agent

    A patient who was started on low molecular weight heparin for suspected DVT, awaiting ultrasound after the weekend, presents to ED with mass

    >
  • x

    Anatomical Course of the Phrenic Nerve

    A 31 year old male presents to ED with a penetrating wound to the neck. Imaging shows damage to the structure which runs down the neck on th

    >
  • Function of Parathyroid Hormone

    You are reviewing a patient with hypocalcaemia secondary to hypoparathyroidism. Parathyroid hormone (PTH) acts to increased calcium reabsorp

    >
  • Heparin: Pharmacology

    Unfractionated heparin therapy is monitored using which of the following:

    >
  • Fusidic Acid: Indications

    Fusidic acid is primarily indicated for infections caused by which of the following microorganisms:

    >
  • Function of the Loop of Henle

    In which part of the loop of Henle is Na+ reabsorbed via the Na+/K+/2Cl- symporter:

    >
  • x

    Action Potential of the Sinoatrial Node

    What is the threshold potential of the sinoatrial node:

    >
  • Clinical Effects of Shoulder Joint Dislocation

    A 28 year old man is brought to ED with a severely painful arm after being involved in a collapsed scrum during a rugby match. An x-ray of h

    >
  • Function of Intrinsic Factor

    Intrinsic factor is vital for gastrointestinal absorption of which of the following:

    >
  • Haemophilia

    Haemophilia B results from a deficiency in:

    >
  • x

    Sickle Cell Disease

    Regarding sickle cell anaemia, which of the following statements is CORRECT:

    >
  • x

    Branches of the Mandibular Nerve

    The inferior alveolar nerve supplies all of the following EXCEPT for the:

    >
  • Production of the Thyroid Hormones

    Regarding the thyroid hormones, which of the following statements is CORRECT:

    >
  • Types of Pathogen

    Which of the following organisms is an opportunistic pathogen:

    >
  • x

    Anatomical Course of the Popliteal Artery

    A 67 year old man presents to the ED complaining of swelling to the posterior knee. On examination you note a pulsatile mass in popliteal f

    >
  • x

    Etomidate: Side Effects

    Which of the following is NOT a common effect of etomidate:

    >
  • Benzodiazepines: Contraindications

    Which of the following is NOT a contraindication to the use of diazepam:

    >
  • Origin of the Axillary Nerve

    A 23 year old man presents to the ED complaining of difficulty moving his left arm. On examination you note weakness of abduction of the sho

    >
  • x

    Clinical Features of Psittacosis

    A 24-year-old pigeon fancier presents with fever of 40°C, severe diffuse headache, malaise, dry hacking cough and muscle aches. Lung exam r

    >
  • Sodium Chloride 0.9% Solution: Composition

    Normal saline (sodium chloride 0.9%) contains how much sodium:

    >
  • Production of Saliva

    At rest, saliva is produced predominantly by which of the following:

    >
  • Functional Unit of the Liver

    Regarding the liver, which of the following statements is INCORRECT:

    >
  • Intraperitoneal vs Retroperitoneal Organs

    A patient is brought to ED following a road traffic collision. CT demonstrates retroperitoneal haemorrhage. Which of the following structure

    >
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