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Anatomy

Upper Limb

Question 45 of 180

A 29 year old patient has sustained a laceration to his arm and damaged the nerve that lies medially in the antecubital fossa. What loss of function would you expect to see in this patient:

Answer:

A proximal median nerve lesion at the elbow may occur due to supracondylar fracture of the humerus or from deep penetrating wounds to the arm. Flexion, abduction and opposition of the thumb at the MCPJ and IPJ are lost due to paralysis of the thenar muscles and the flexor pollicis longus.

Median Nerve Injury

Table: Clinical Features of Median Nerve Injury

Lesion Proximal (arm, elbow, proximal forearm) Distal (wrist)
Mechanisms Supracondylar fracture, stab wound to arm or forearm Lacerations just proximal to flexor retinaculum
Motor Loss Forearm pronation, wrist flexion and abduction, index and middle finger flexion, thumb flexion, abduction and opposition Thumb flexion, abduction and opposition, flexion of index and middle finger MCPJ
Sensory Loss Lateral aspect of palm and palmar surface and fingertips of lateral three and a half digits Palmar surface and fingertips of lateral three and a half digits
Signs Forearm rests in supination with wrist in ulnar deviation and thumb extended, thenar eminence wasting, hand of Benediction (when asked to make a fist, the patient will be able to flex the little and ring fingers but not the index and middle fingers) Thenar eminence wasting

Proximal Median Nerve Injury

MECHANISM OF INJURY:

A proximal median nerve lesion at the elbow may occur due to supracondylar fracture of the humerus or from deep penetrating wounds to the arm.

CLINICAL FEATURES:

  • Pronation of the forearm and flexion and abduction of the wrist are lost due to paralysis of the flexors and pronators in the forearm. The forearm thus often rests in supination with ulnar deviation of the wrist (due to unopposed action of the flexor carpi ulnaris).
  • Flexion, abduction and opposition of the thumb at the MCPJ and IPJ are lost due to paralysis of the thenar muscles and the flexor pollicis longus.
  • Flexion of the index and middle fingers at the IPJs is lost due to paralysis of the flexor digitorum superficialis and the lateral half of the flexor digitorum profundus.
  • Extension of the index and middle fingers at the IPJs is weakened due to paralysis of the lateral two lumbrical muscles (but not lost due to preservation of the interossei innervated by the ulnar nerve)
  • Flexion of the MCPJ of the index and middle fingers is lost due to paralysis of the lateral two lumbrical muscles.
  • N.B. Flexion of the ring and little fingers at the MCPJ and DIPJ are preserved as these are functions of the medial half of the flexor digitorum profundus and the medial two lumbrical muscles, innervated by the ulnar nerve (there may be weakness of flexion at the PIPJ of these fingers due to paralysis of the flexor digitorum superficialis).
  • There is loss of sensation over the lateral aspect of the palm, and the skin over the palmar surface and fingertips of the lateral three and a half digits.

Distal Median Nerve Injury

MECHANISM OF INJURY:

Medial nerve lesion at the wrist often occurs due to lacerations just proximal to the flexor retinaculum. Only the intrinsic hand muscles are affected.

CLINICAL FEATURES:

  • Loss of opposition, abduction and flexion of the MCPJ of the thumb occurs due to paralysis of the thenar muscles.
  • Loss of flexion at the MCPJ of the index and middle finger and weakness of extension at the IPJs of the index and middle finger occurs due to paralysis of the lateral two lumbricals.
  • There is loss of sensation to the palmar surface and fingertips of the lateral three and a half digits.

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  • Biochemistry
  • Blood Gases
  • Haematology
Biochemistry Normal Value
Sodium 135 – 145 mmol/l
Potassium 3.0 – 4.5 mmol/l
Urea 2.5 – 7.5 mmol/l
Glucose 3.5 – 5.0 mmol/l
Creatinine 35 – 135 μmol/l
Alanine Aminotransferase (ALT) 5 – 35 U/l
Gamma-glutamyl Transferase (GGT) < 65 U/l
Alkaline Phosphatase (ALP) 30 – 135 U/l
Aspartate Aminotransferase (AST) < 40 U/l
Total Protein 60 – 80 g/l
Albumin 35 – 50 g/l
Globulin 2.4 – 3.5 g/dl
Amylase < 70 U/l
Total Bilirubin 3 – 17 μmol/l
Calcium 2.1 – 2.5 mmol/l
Chloride 95 – 105 mmol/l
Phosphate 0.8 – 1.4 mmol/l
Haematology Normal Value
Haemoglobin 11.5 – 16.6 g/dl
White Blood Cells 4.0 – 11.0 x 109/l
Platelets 150 – 450 x 109/l
MCV 80 – 96 fl
MCHC 32 – 36 g/dl
Neutrophils 2.0 – 7.5 x 109/l
Lymphocytes 1.5 – 4.0 x 109/l
Monocytes 0.3 – 1.0 x 109/l
Eosinophils 0.1 – 0.5 x 109/l
Basophils < 0.2 x 109/l
Reticulocytes < 2%
Haematocrit 0.35 – 0.49
Red Cell Distribution Width 11 – 15%
Blood Gases Normal Value
pH 7.35 – 7.45
pO2 11 – 14 kPa
pCO2 4.5 – 6.0 kPa
Base Excess -2 – +2 mmol/l
Bicarbonate 24 – 30 mmol/l
Lactate < 2 mmol/l

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