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Anatomy

Thorax

Question 25 of 180

A 68 year old man presents to ED with sudden onset severe chest pain and is found to suffered a myocardial infarction in the area of the apex of the heart. Occlusion of which of the following blood vessels is most likely responsible:

Answer:

The apex of the heart is primarily supplied by the anterior interventricular branch of the left coronary artery.

Cardiac Blood Supply

The right and left coronary arteries arise from the right and left aortic sinuses in the initial portion of the ascending aorta and supply the muscle and other tissues of the heart.

Territories of Supply

Although there is variation, in most people the territories of supply are as follows:

The right coronary artery supplies:

  • the right atrium
  • most of the right ventricle
  • the sinoatrial and atrioventricular nodes
  • the interatrial septum
  • a portion of the left atrium
  • the posteroinferior one-third of the interventricular septum
  • a portion of the posterior part of the left ventricle

The left coronary artery supplies:

  • most of the left atrium
  • most of the left ventricle
  • a portion of the right ventricle
  • most of the interventricular septum (including the atrioventricular bundle and branches)

Branches

Table: Blood Supply of the Heart

Artery Territory of Supply
Right coronary artery Right atrium and ventricle, sinoatrial node, atrioventricular node
Right marginal branch Inferior aspect of right ventricle
Posterior interventricular branch Posterior aspect of right and left ventricles, posterior one-third of interventricular septum
Left coronary artery Via main branches below
Anterior interventricular branch Right and left ventricles, anterior two-thirds of interventricular septum
Left circumflex branch Left atrium and left ventricle

The right coronary artery supplies the right atrium, the sinoatrial node and the atrioventricular node (via the SA and AV nodal branches) and gives rise to two principal branches:

  • the right marginal branch (supplying the inferior margin of the right ventricle and the apex)
  • the posterior interventricular branch (supplying the posterior aspect of the right and left ventricles and the posterior one-third of the interventricular septum).

The left coronary artery gives rise to two principal branches:

  • the anterior interventricular branch (supplying the right and left ventricles, the apex and the anterior two-thirds of the interventricular septum)
  • the circumflex branch (supplying the left atrium and left ventricle).

By OpenStax College [CC BY 3.0 , via Wikimedia Commons

Cardiac Blood Supply. (Image by OpenStax College [CC BY 3.0 , via Wikimedia Commons)

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  • Biochemistry
  • Blood Gases
  • Haematology
Biochemistry Normal Value
Sodium 135 – 145 mmol/l
Potassium 3.0 – 4.5 mmol/l
Urea 2.5 – 7.5 mmol/l
Glucose 3.5 – 5.0 mmol/l
Creatinine 35 – 135 μmol/l
Alanine Aminotransferase (ALT) 5 – 35 U/l
Gamma-glutamyl Transferase (GGT) < 65 U/l
Alkaline Phosphatase (ALP) 30 – 135 U/l
Aspartate Aminotransferase (AST) < 40 U/l
Total Protein 60 – 80 g/l
Albumin 35 – 50 g/l
Globulin 2.4 – 3.5 g/dl
Amylase < 70 U/l
Total Bilirubin 3 – 17 μmol/l
Calcium 2.1 – 2.5 mmol/l
Chloride 95 – 105 mmol/l
Phosphate 0.8 – 1.4 mmol/l
Haematology Normal Value
Haemoglobin 11.5 – 16.6 g/dl
White Blood Cells 4.0 – 11.0 x 109/l
Platelets 150 – 450 x 109/l
MCV 80 – 96 fl
MCHC 32 – 36 g/dl
Neutrophils 2.0 – 7.5 x 109/l
Lymphocytes 1.5 – 4.0 x 109/l
Monocytes 0.3 – 1.0 x 109/l
Eosinophils 0.1 – 0.5 x 109/l
Basophils < 0.2 x 109/l
Reticulocytes < 2%
Haematocrit 0.35 – 0.49
Red Cell Distribution Width 11 – 15%
Blood Gases Normal Value
pH 7.35 – 7.45
pO2 11 – 14 kPa
pCO2 4.5 – 6.0 kPa
Base Excess -2 – +2 mmol/l
Bicarbonate 24 – 30 mmol/l
Lactate < 2 mmol/l

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