← Back to Session

Time Completed: 01:08:33

Final Score 46%

83
97

Questions

  • Q1. Correct
  • Q2. X Incorrect
  • Q3. Correct
  • Q4. Correct
  • Q5. X Incorrect
  • Q6. Correct
  • Q7. X Incorrect
  • Q8. Correct
  • Q9. X Incorrect
  • Q10. Correct
  • Q11. Correct
  • Q12. Correct
  • Q13. Correct
  • Q14. Correct
  • Q15. X Incorrect
  • Q16. X Incorrect
  • Q17. Correct
  • Q18. X Incorrect
  • Q19. Correct
  • Q20. X Incorrect
  • Q21. X Incorrect
  • Q22. Correct
  • Q23. Correct
  • Q24. X Incorrect
  • Q25. Correct
  • Q26. Correct
  • Q27. Correct
  • Q28. X Incorrect
  • Q29. X Incorrect
  • Q30. X Incorrect
  • Q31. Correct
  • Q32. X Incorrect
  • Q33. X Incorrect
  • Q34. Correct
  • Q35. X Incorrect
  • Q36. X Incorrect
  • Q37. Correct
  • Q38. X Incorrect
  • Q39. X Incorrect
  • Q40. X Incorrect
  • Q41. Correct
  • Q42. X Incorrect
  • Q43. Correct
  • Q44. X Incorrect
  • Q45. Correct
  • Q46. X Incorrect
  • Q47. X Incorrect
  • Q48. X Incorrect
  • Q49. X Incorrect
  • Q50. Correct
  • Q51. Correct
  • Q52. Correct
  • Q53. Correct
  • Q54. Correct
  • Q55. X Incorrect
  • Q56. Correct
  • Q57. Correct
  • Q58. X Incorrect
  • Q59. Correct
  • Q60. Correct
  • Q61. X Incorrect
  • Q62. X Incorrect
  • Q63. X Incorrect
  • Q64. X Incorrect
  • Q65. X Incorrect
  • Q66. X Incorrect
  • Q67. Correct
  • Q68. X Incorrect
  • Q69. Correct
  • Q70. X Incorrect
  • Q71. Correct
  • Q72. Correct
  • Q73. X Incorrect
  • Q74. Correct
  • Q75. X Incorrect
  • Q76. X Incorrect
  • Q77. Correct
  • Q78. Correct
  • Q79. X Incorrect
  • Q80. X Incorrect
  • Q81. Correct
  • Q82. X Incorrect
  • Q83. X Incorrect
  • Q84. Correct
  • Q85. X Incorrect
  • Q86. X Incorrect
  • Q87. Correct
  • Q88. X Incorrect
  • Q89. Correct
  • Q90. Correct
  • Q91. X Incorrect
  • Q92. Correct
  • Q93. X Incorrect
  • Q94. X Incorrect
  • Q95. X Incorrect
  • Q96. Correct
  • Q97. X Incorrect
  • Q98. Correct
  • Q99. X Incorrect
  • Q100. Correct
  • Q101. X Incorrect
  • Q102. Correct
  • Q103. X Incorrect
  • Q104. X Incorrect
  • Q105. X Incorrect
  • Q106. X Incorrect
  • Q107. Correct
  • Q108. X Incorrect
  • Q109. Correct
  • Q110. X Incorrect
  • Q111. X Incorrect
  • Q112. Correct
  • Q113. X Incorrect
  • Q114. Correct
  • Q115. Correct
  • Q116. Correct
  • Q117. X Incorrect
  • Q118. Correct
  • Q119. X Incorrect
  • Q120. Correct
  • Q121. Correct
  • Q122. Correct
  • Q123. Correct
  • Q124. Correct
  • Q125. X Incorrect
  • Q126. Correct
  • Q127. X Incorrect
  • Q128. X Incorrect
  • Q129. Correct
  • Q130. Correct
  • Q131. X Incorrect
  • Q132. X Incorrect
  • Q133. X Incorrect
  • Q134. X Incorrect
  • Q135. X Incorrect
  • Q136. Correct
  • Q137. Correct
  • Q138. X Incorrect
  • Q139. X Incorrect
  • Q140. Correct
  • Q141. Correct
  • Q142. X Incorrect
  • Q143. Correct
  • Q144. X Incorrect
  • Q145. X Incorrect
  • Q146. X Incorrect
  • Q147. X Incorrect
  • Q148. X Incorrect
  • Q149. X Incorrect
  • Q150. Correct
  • Q151. X Incorrect
  • Q152. X Incorrect
  • Q153. Correct
  • Q154. X Incorrect
  • Q155. X Incorrect
  • Q156. X Incorrect
  • Q157. Correct
  • Q158. Correct
  • Q159. X Incorrect
  • Q160. X Incorrect
  • Q161. Correct
  • Q162. X Incorrect
  • Q163. X Incorrect
  • Q164. Correct
  • Q165. X Incorrect
  • Q166. X Incorrect
  • Q167. Correct
  • Q168. Correct
  • Q169. X Incorrect
  • Q170. X Incorrect
  • Q171. Correct
  • Q172. Correct
  • Q173. Correct
  • Q174. X Incorrect
  • Q175. Correct
  • Q176. Correct
  • Q177. Correct
  • Q178. X Incorrect
  • Q179. X Incorrect
  • Q180. X Incorrect

Physiology

Gastrointestinal

Question 43 of 180

Regarding the liver, which of the following statements is INCORRECT:

Answer:

The liver consists of four lobes, each made up of hexagonal lobules, the functional unit of the liver. Each lobule consists of a central vein that eventually becomes part of the hepatic vein. Surrounding the central vein are single columns of hepatocytes radiating outwards; between the hepatocytes are small canaliculi which drain into the bile duct on the periphery of the lobule. At each of the six corners of the lobules lies a 'portal triad' comprising branches of the hepatic artery, the portal vein and the bile duct.

Functional Anatomy

The liver consists of four lobes, each made up of hexagonal lobules, the functional unit of the liver. Each lobule consists of a central vein that eventually becomes part of the hepatic vein. Surrounding the central vein are single columns of hepatocytes radiating outwards; between the hepatocytes are small canaliculi which drain into the bile duct on the periphery of the lobule. At each of the six corners of the lobules lies a 'portal triad' comprising branches of the hepatic artery, the portal vein and the bile duct.

By OpenStax College [CC BY 3.0 , via Wikimedia Commons

Functional Anatomy of the Liver. (Image by OpenStax College [CC BY 3.0 , via Wikimedia Commons)

Functions

The main functions of the liver are:

  • Foetal haematopoiesis
  • Protein metabolism
    • synthesis and secretion of albumin, synthesis of plasma proteins, formation of urea from ammonia, deamination of amino acids, synthesis of coagulation factors, metabolism of polypeptide hormones
  • Fat metabolism
    • formation of lipoproteins and fatty acids, synthesis of cholesterol, conversion of cholesterol to bile salts, conversion of carbohydrates and protein to fat ketogenesis, metabolism and excretion of steroid hormones
  • Carbohydrate metabolism
    • gluconeogenesis, glycogenesis, glycogenolysis
  • Bile production
    • synthesis of bile salts, production of alkaline fluid for neutralisation of gastric acid in the intestines, excretion of waste metabolites and detoxified substances from the body in bile
  • Storage of vitamins and minerals
    • folate, B12, fat-soluble vitamins, iron, copper
  • Bone metabolism in the form of hydroxylation of vitamin D
  • Biotransformation and detoxification of drugs and exogenous substances, steroid hormones and nitrogenous gut toxins
  • Protection by filtration of portal blood
  • Phagocytosis of bacteria/antigens by Kupffer cells

Report A Problem

Is there something wrong with this question? Let us know and we’ll fix it as soon as possible.

Loading Form...

Close
  • Biochemistry
  • Blood Gases
  • Haematology
Biochemistry Normal Value
Sodium 135 – 145 mmol/l
Potassium 3.0 – 4.5 mmol/l
Urea 2.5 – 7.5 mmol/l
Glucose 3.5 – 5.0 mmol/l
Creatinine 35 – 135 μmol/l
Alanine Aminotransferase (ALT) 5 – 35 U/l
Gamma-glutamyl Transferase (GGT) < 65 U/l
Alkaline Phosphatase (ALP) 30 – 135 U/l
Aspartate Aminotransferase (AST) < 40 U/l
Total Protein 60 – 80 g/l
Albumin 35 – 50 g/l
Globulin 2.4 – 3.5 g/dl
Amylase < 70 U/l
Total Bilirubin 3 – 17 μmol/l
Calcium 2.1 – 2.5 mmol/l
Chloride 95 – 105 mmol/l
Phosphate 0.8 – 1.4 mmol/l
Haematology Normal Value
Haemoglobin 11.5 – 16.6 g/dl
White Blood Cells 4.0 – 11.0 x 109/l
Platelets 150 – 450 x 109/l
MCV 80 – 96 fl
MCHC 32 – 36 g/dl
Neutrophils 2.0 – 7.5 x 109/l
Lymphocytes 1.5 – 4.0 x 109/l
Monocytes 0.3 – 1.0 x 109/l
Eosinophils 0.1 – 0.5 x 109/l
Basophils < 0.2 x 109/l
Reticulocytes < 2%
Haematocrit 0.35 – 0.49
Red Cell Distribution Width 11 – 15%
Blood Gases Normal Value
pH 7.35 – 7.45
pO2 11 – 14 kPa
pCO2 4.5 – 6.0 kPa
Base Excess -2 – +2 mmol/l
Bicarbonate 24 – 30 mmol/l
Lactate < 2 mmol/l

Join our Newsletter

Stay updated with free revision resources and exclusive discounts

©2017 - 2024 MRCEM Success