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Questions Answered: 26

Final Score 46%

12
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Anatomy

Upper Limb

Question 125 of 180

A 54 year old woman presents to ED having sustained a laceration to the palm of her hand while gardening. She is unable to oppose her thumb, but sensation is intact. Which of the following nerves has most likely been injured:

Answer:

The recurrent branch of the median nerve innervates the thenar muscles (flexor pollicis brevis, abductor pollicis brevis, opponens pollicis) and has no sensory function. Damage to this nerve results in weakness of abduction, opposition and flexion of the thumb. The anterior interosseous nerve is a branch of the median nerve and innervates the deep muscles of the anterior forearm - damage to this nerve would result in weakness of thumb flexion but not opposition as described in this patient.

The median nerve is formed from the medial and lateral brachial plexus cords and contains fibres from all five roots (C5 - T1).

Table: Anatomical Overview of the Median Nerve

Nerve Median
Nerve roots C5 – T1
Plexus cords Medial and lateral cords
Motor Supply All the anterior forearm muscles (except for the flexor carpi ulnaris and the medial half of the flexor digitorum profundus), the thenar muscles (flexor pollicis brevis, abductor pollicis brevis, opponens pollicis) and the lateral two lumbricals
Sensory supply Lateral aspect of palm and palmar surface and fingertips of lateral three and a half digits

Anatomical course

The median nerve originates in the axilla before passing down the medial side of the arm (initially lateral to the brachial artery before crossing over to the medial side of the brachial artery). It enters the anterior compartment of the forearm via the antecubital fossa, travelling between the flexor digitorum profundus and flexor digitorum superficialis muscles, before entering the hand via the carpal tunnel and bifurcating into its terminal branches.

By Henry Vandyke Carter [Public domain], via Wikimedia Commons

Median Nerve. (Image by Henry Vandyke Carter [Public domain], via Wikimedia Commons)

Branches

Table: Branches of the Median Nerve

Branches of Median Nerve Origin Supply
Median nerve Axilla Superficial and intermediate compartment of anterior forearm (pronator teres, flexor carpi radialis, palmaris longus, flexor digitorum superficialis, NOT flexor carpi ulnaris)
Anterior interosseous nerve Forearm Deep compartment of anterior forearm (flexor pollicis longus, pronator quadratus, lateral half of flexor digitorum profundus)
Palmar cutaneous branch Forearm Skin over the lateral aspect of the palm
Recurrent branch of median nerve Hand Thenar muscles (flexor pollicis brevis, abductor pollicis brevis, opponens pollicis)
Palmar digital branch Hand Lateral two lumbricals and skin over the palmar surface and fingertips of the lateral three and a half digits

The median nerve directly innervates the pronator teres, the flexor carpi radialis, the palmaris longus and the flexor digitorum superficialis. It gives off no major branches in the arm, but gives rise to the anterior interosseous nerve (innervating the flexor pollicis longus, the pronator quadratus, and the lateral half of the flexor digitorum profundus) and the palmar cutaneous nerve (innervating the lateral aspect of the palm) in the forearm.

In the hand the median nerve bifurcates into the recurrent branch of the median nerve (innervating the thenar muscles) and the palmar digital branch (innervating the lateral two lumbricals and the skin over the palmar surface and fingertips of the lateral three and a half digits).

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  • Biochemistry
  • Blood Gases
  • Haematology
Biochemistry Normal Value
Sodium 135 – 145 mmol/l
Potassium 3.0 – 4.5 mmol/l
Urea 2.5 – 7.5 mmol/l
Glucose 3.5 – 5.0 mmol/l
Creatinine 35 – 135 μmol/l
Alanine Aminotransferase (ALT) 5 – 35 U/l
Gamma-glutamyl Transferase (GGT) < 65 U/l
Alkaline Phosphatase (ALP) 30 – 135 U/l
Aspartate Aminotransferase (AST) < 40 U/l
Total Protein 60 – 80 g/l
Albumin 35 – 50 g/l
Globulin 2.4 – 3.5 g/dl
Amylase < 70 U/l
Total Bilirubin 3 – 17 μmol/l
Calcium 2.1 – 2.5 mmol/l
Chloride 95 – 105 mmol/l
Phosphate 0.8 – 1.4 mmol/l
Haematology Normal Value
Haemoglobin 11.5 – 16.6 g/dl
White Blood Cells 4.0 – 11.0 x 109/l
Platelets 150 – 450 x 109/l
MCV 80 – 96 fl
MCHC 32 – 36 g/dl
Neutrophils 2.0 – 7.5 x 109/l
Lymphocytes 1.5 – 4.0 x 109/l
Monocytes 0.3 – 1.0 x 109/l
Eosinophils 0.1 – 0.5 x 109/l
Basophils < 0.2 x 109/l
Reticulocytes < 2%
Haematocrit 0.35 – 0.49
Red Cell Distribution Width 11 – 15%
Blood Gases Normal Value
pH 7.35 – 7.45
pO2 11 – 14 kPa
pCO2 4.5 – 6.0 kPa
Base Excess -2 – +2 mmol/l
Bicarbonate 24 – 30 mmol/l
Lactate < 2 mmol/l

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