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Anatomy

Cranial Nerve Lesions

Question 71 of 180

Regarding the accessory nerve, which of the following statements is INCORRECT:

Answer:

Accessory nerve palsy results in inability to shrug the shoulders and to rotate the head to look at the opposite side to the lesion.

Cranial Nerve XI: Spinal Accessory Nerve

The spinal accessory nerve (CN XI) is primarily a motor nerve innervating the sternocleidomastoid and the trapezius muscles which mediate head and shoulder movement.

Table: Overview of the Spinal Accessory Nerve

Cranial Nerve Spinal Accessory Nerve (CN XI)
Key anatomy Originates from cervical segments C1 – C5/C6, enters cranial cavity through foramen magnum, travels through posterior cranial fossa and exits skull through jugular foramen
Function Motor: sternocleidomastoid, trapezius
Assessment Test head rotation and shoulder shrug against resistance
Clinical effects of injury Inability to shrug ipsilateral shoulder, shoulder droop, inability to rotate head towards opposite side to the lesion
Causes of injury Metastatic lymphadenopathy in neck, neck dissection surgery, internal jugular vein cannulation, blunt or penetrating neck trauma

Anatomical Course

It is a unique cranial nerve because its roots actually arise from motor neurons in the upper five segments of the cervical spinal cord. The fibres leave the lateral surface of the spinal cord, joining together as they ascend, and enter the cranial cavity through the foramen magnum forming the accessory nerve. The accessory nerve then continues through the posterior cranial fossa and exits the skull through the jugular foramen before descending in the neck along the internal carotid artery to innervate the muscles.

Spinal Accessory Nerve. (Image by Henry Vandyke Carter [Public domain], via Wikimedia Commons)

A few rootlets arising from the medulla just inferior to the fibres that arise to form the vagus nerve, may be referred to as the 'cranial' roots of the accessory nerve. Leaving the medulla these fibres course with the 'spinal' roots of the accessory nerve into the jugular foramen, at which point these cranial roots join the vagus nerve. They are distributed to the pharyngeal musculature innervated by the vagus nerve and are therefore usually described as being part of the vagus nerve.

Assessment

The spinal accessory nerve is assessed by:

  • Testing the sternocleidomastoid by asking the patient to turn their head to each side against resistance
  • Testing the trapezius by asking the patient to shrug their shoulders against resistance

Likely Causes of Disease or Injury

Damage can occur due to:

  • Metastatic disease in the neck with lymph node involvement
  • Neck dissection surgery
  • Cannulation of the internal jugular vein
  • Blunt or penetrating neck trauma

Common Clinical Effects

Clinical features of CN XI palsy include muscle wasting and paralysis of the sternocleidomastoid and trapezius muscles resulting in the inability to rotate the head to the side opposite the lesion and to shrug the ipsilateral shoulder (resulting in shoulder droop) respectively.

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  • Biochemistry
  • Blood Gases
  • Haematology
Biochemistry Normal Value
Sodium 135 – 145 mmol/l
Potassium 3.0 – 4.5 mmol/l
Urea 2.5 – 7.5 mmol/l
Glucose 3.5 – 5.0 mmol/l
Creatinine 35 – 135 μmol/l
Alanine Aminotransferase (ALT) 5 – 35 U/l
Gamma-glutamyl Transferase (GGT) < 65 U/l
Alkaline Phosphatase (ALP) 30 – 135 U/l
Aspartate Aminotransferase (AST) < 40 U/l
Total Protein 60 – 80 g/l
Albumin 35 – 50 g/l
Globulin 2.4 – 3.5 g/dl
Amylase < 70 U/l
Total Bilirubin 3 – 17 μmol/l
Calcium 2.1 – 2.5 mmol/l
Chloride 95 – 105 mmol/l
Phosphate 0.8 – 1.4 mmol/l
Haematology Normal Value
Haemoglobin 11.5 – 16.6 g/dl
White Blood Cells 4.0 – 11.0 x 109/l
Platelets 150 – 450 x 109/l
MCV 80 – 96 fl
MCHC 32 – 36 g/dl
Neutrophils 2.0 – 7.5 x 109/l
Lymphocytes 1.5 – 4.0 x 109/l
Monocytes 0.3 – 1.0 x 109/l
Eosinophils 0.1 – 0.5 x 109/l
Basophils < 0.2 x 109/l
Reticulocytes < 2%
Haematocrit 0.35 – 0.49
Red Cell Distribution Width 11 – 15%
Blood Gases Normal Value
pH 7.35 – 7.45
pO2 11 – 14 kPa
pCO2 4.5 – 6.0 kPa
Base Excess -2 – +2 mmol/l
Bicarbonate 24 – 30 mmol/l
Lactate < 2 mmol/l

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