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Questions Answered: 122

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Physiology

Cardiovascular

Question 98 of 122

Regarding the lymphatic system, which of the following statements is CORRECT:

Answer:

Normally, filtration of fluid out of the capillaries is slightly greater than absorption of fluid into the capillaries. Fluid filtered by the microcirculation (about 8 L per day) is returned to the circulation by the lymphatic system. Lymphatic capillaries drain into collecting lymphatics and then into larger lymphatic vessels, both containing smooth muscle and unidirectional valves. From here, lymph is propelled by smooth muscle constriction and compression of the vessels by body movements into afferent lymphatics and then the lymph nodes, where bacteria and other foreign materials are removed by phagocytes. Most fluid is reabsorbed here by capillaries, with the remainder returning via efferent lymphatics and the thoracic duct. The lymphatic system plays a major role in the body's immune defence and is also important for absorption and transport of fats.

Normally, filtration of fluid out of the capillaries is slightly greater than absorption of fluid into the capillaries. Fluid filtered by the microcirculation (about 8 L per day) is returned to the circulation by the lymphatic system.

Lymphatic capillaries are blind-ended tubes walled with endothelial cells which allow the entry of fluid, protein and bacteria, but prevent their exit. Lymphatic capillaries drain into collecting lymphatics and then into larger lymphatic vessels, both containing smooth muscle and unidirectional valves.

From here, lymph is propelled by smooth muscle constriction and compression of the vessels by body movements into afferent lymphatics and then the lymph nodes, where bacteria and other foreign materials are removed by phagocytes. Most fluid is reabsorbed here by capillaries, with the remainder returning via efferent lymphatics and the thoracic duct into the subclavian veins.

The lymphatic system plays a major role in the body's immune defence and is also important for absorption and transport of fats.

Via Wikimedia Commons

Lymphatic Capillaries. (Image by OpenStax College [CC BY 3.0 (https://creativecommons.org/licenses/by/3.0)], via Wikimedia Commons)

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  • Biochemistry
  • Blood Gases
  • Haematology
Biochemistry Normal Value
Sodium 135 – 145 mmol/l
Potassium 3.0 – 4.5 mmol/l
Urea 2.5 – 7.5 mmol/l
Glucose 3.5 – 5.0 mmol/l
Creatinine 35 – 135 μmol/l
Alanine Aminotransferase (ALT) 5 – 35 U/l
Gamma-glutamyl Transferase (GGT) < 65 U/l
Alkaline Phosphatase (ALP) 30 – 135 U/l
Aspartate Aminotransferase (AST) < 40 U/l
Total Protein 60 – 80 g/l
Albumin 35 – 50 g/l
Globulin 2.4 – 3.5 g/dl
Amylase < 70 U/l
Total Bilirubin 3 – 17 μmol/l
Calcium 2.1 – 2.5 mmol/l
Chloride 95 – 105 mmol/l
Phosphate 0.8 – 1.4 mmol/l
Haematology Normal Value
Haemoglobin 11.5 – 16.6 g/dl
White Blood Cells 4.0 – 11.0 x 109/l
Platelets 150 – 450 x 109/l
MCV 80 – 96 fl
MCHC 32 – 36 g/dl
Neutrophils 2.0 – 7.5 x 109/l
Lymphocytes 1.5 – 4.0 x 109/l
Monocytes 0.3 – 1.0 x 109/l
Eosinophils 0.1 – 0.5 x 109/l
Basophils < 0.2 x 109/l
Reticulocytes < 2%
Haematocrit 0.35 – 0.49
Red Cell Distribution Width 11 – 15%
Blood Gases Normal Value
pH 7.35 – 7.45
pO2 11 – 14 kPa
pCO2 4.5 – 6.0 kPa
Base Excess -2 – +2 mmol/l
Bicarbonate 24 – 30 mmol/l
Lactate < 2 mmol/l

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