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  • Pharmacological Management of DKA

    Regarding the management of diabetic ketoacidosis (DKA), insulin infusion may be stopped after which of the following:

    >
  • Diagnosis of Diabetes Mellitus

    Which of the following is typically used as the cut off for diagnosing diabetes mellitus:

    >
  • Function of the Pituitary Gland

    Which of the following hormones is NOT secreted by the anterior pituitary gland:

    >
  • x

    Cutaneous Innervation of the Face

    The area of skin over the prominence of the cheekbone is primarily supplied by which of the following nerves:

    >
  • Function of the Adrenal Medulla

    Regarding the adrenal medulla, which of the following statements is INCORRECT:

    >
  • Functional Anatomy of the Nephron

    The renal corpuscle, consisting of the Bowman's capsule and the glomerulus is found where in the kidney:

    >
  • Increased vs Normal Anion Gap

    Which of the following is typically a cause of a normal anion gap metabolic acidosis:

    >
  • Interpretation of Box and Whisker Plots

    Regarding the following box and whisker plot, what percentage of data values lie between 6 and 16.

    >
  • Calculation of Cardiac Output

    The cardiac output in a healthy adult male at rest is usually about:

    >
  • Characteristics of the Skeletal Muscle Circulation

    Regarding the skeletal muscle circulation, which of the following statements is CORRECT:

    >
  • x

    Cortical Areas of the Parietal Lobe

    The primary somatosensory cortex is located in which of the following regions:

    >
  • Paracetamol: Pharmacology

    Regarding paracetamol, which of the following statements is CORRECT:

    >
  • Location of Wernicke's Area

    The Wernicke's speech area is located in which of the following regions:

    >
  • Osmolarity vs Osmolality

    Which of the following is the equation for calculating serum osmolality:

    >
  • Pathogenesis of Tetanus

    Regarding Clostridium tetani, which of the following statements is CORRECT:

    >
  • Clinical Features of Bronchiolitis

    A 9 month old baby is brought into the ED with a one day history of wheezing and dyspnoea. She is having difficulty feeding due to her breat

    >
  • Cutaneous Innervation of the Upper Limb

    You have been asked to review a patient in the Minor Injuries Unit. The 32 year old sustained a laceration to the forearm during a fight. He

    >
  • Clinical Effects of Facial Nerve Lesion

    A 21 year old female presents to ED with isolated facial nerve palsy. You diagnose Bell's palsy. Which of the following clinical features mi

    >
  • Management of Community Aquired Pneumonia

    A 55 year old man, usually fit and well, presents to ED complaining of a cough productive of green sputum, fever and feeling tight-chested 

    >
  • Clinical Effects of Frontal Lobe Lesion

    Which of the following clinical features would you LEAST expect to see in a lesion of the frontal lobe:

    >
  • Nifedipine: Side Effects

    Which of the following is a common side effect of nifedipine:

    >
  • Clinical Effects of Frontal Lobe Lesion

    A 55 year old woman presents to ED complaining of headaches. On examination the patient is found to have weakness of the left side of her bo

    >
  • Distribution of Myotomes

    A 68 year old lady was involved in a road traffic accident and describes a whiplash type injury. She has pain and tenderness in the cervical

    >
  • Pathway of the Gag Reflex

    Which of the following nerves is the efferent pathway of the gag reflex:

    >
  • x

    Anatomical Relations of the Colon

    Which of the following structures is NOT a posterior relation of the transverse colon:

    >
  • Anatomical Relations of the Common Bile Duct

    A 65 year old man presents to ED complaining of abdominal pain, jaundice and weight loss. Imaging shows a tumour of the head of the pancreas

    >
  • Definition of Type II Error

    A type II error occurs when:

    >
  • x

    Function of the Membrane Proteins

    Regarding cell signalling, which of the following statements is INCORRECT:

    >
  • Anaemia Overview

    Which of the following does NOT typically cause a normocytic anaemia:

    >
  • Clinical Effects of Hyperkalaemia

    Which of the following is an ECG change typically associated with hyperkalaemia:

    >
  • Anatomy of the Vertebral Canal

    A 19 year old student presents to ED with a headache, fever and photophobia. You suspect meningitis and agree to observe your junior perform

    >
  • Calculation of Specificity

    The results from the study investigating the accuracy of a new diagnostic test can be displayed in the following format. How is the specif

    >
  • Clinical Features of Primary Hypothyroidism

    Which of the following biochemical patterns would be typical of primary hypothyroidism:

    >
  • Types of Data

    An FY2 in ED is collecting retrospective data for an audit on headache. He records the number of patients with headaches seen per day and fo

    >
  • Function of the Superficial Fibular Nerve

    The superficial fibular nerve supplies which of the following areas of skin:

    >
  • Pulmonary Host Defence Mechanisms

    Which of the following is part of respiratory host defence:

    >
  • x

    Innervation of the Quadratus Lumborum Muscle

    The quadratus lumborum muscle is innervated by which of the following:

    >
  • Carbon Dioxide Transport in the Blood

    Regarding carbon dioxide transport in the blood, which of the following statements is CORRECT:

    >
  • Regulation of Catecholamines

    The chromaffin cells of the adrenal medulla secrete catecholamines, stimulated by which of the following:

    >
  • Cutaneous Innervation of the Upper Limb

    A 65 year old woman presents to the ED complaining of paresthesia in the left arm. On examination you note she has no sensation over the lat

    >
  • Layers of the Neck Fascia

    Regarding the neck fascia, which of the following statements is INCORRECT:

    >
  • Hypersensitivity Reactions

    You are reviewing a patient with an exacerbation of their rheumatoid arthritis. Rheumatoid arthritis is an example of type III hypersensitiv

    >
  • Regulation of Prolactin

    Dopamine released from the hypothalamus acts to cause which of the following:

    >
  • Boundaries of the Femoral Triangle

    You are discussing clinically relevant lower limb anatomy with a group of medical students. The femoral triangle is an important, clinically

    >
  • Complications of Rubella

    A pregnant patient presents to ED with a new onset rash which started on her face and spread to her body. She has recently been in contact w

    >
  • Function of the Medial Pterygoid Muscle

    The medial pterygoid primarily acts to produce which of the following movements:

    >
  • x

    Site of Meckel's Diverticulum

    Which of the following describes the site of a Meckel's diverticulum:

    >
  • Mechanism of Ventilation-Perfusion Mismatch

    Regarding V/Q mismatch, which of the following statements is CORRECT:

    >
  • Pharmacological Management of Hypokalaemia

    Regarding potassium replacement, which of the following statements is INCORRECT:

    >
  • x

    Surface Anatomy of the Duodenum

    The fourth part of the duodenum terminates at which of the following vertebral levels:

    >
  • Clinical Effects of Mandibular Nerve Lesion

    A 56 year old female presents to ED complaining of loss of sensation over the anterior two-thirds of her tongue. Taste and salivation are in

    >
  • Greater vs Lesser Omentum

    The lesser omentum extends between which of the following structures:

    >
  • Management of Tachyarrhythmias

    What is the recommended dosing regime for amiodarone in the treatment of a stable regular broad-complex tachycardia:

    >
  • Regulation of Glomerular Filtration Rate

    In the glomerulus, if the diameter of the afferent arteriole is reduced relative to the diameter of the efferent arteriole:

    >
  • Causative Agents of Neonatal Meningitis

    A one week old infant is brought to ED unwell. She is pyrexic, floppy and unresponsive with a bulging fontanelle. Empirical antibiotics are

    >
  • Characteristics of Neisseria Meningitidis

    Regarding Neisseria meningitidis, which of the following statements is CORRECT:

    >
  • x

    Surface Anatomy of the Heart Valves

    Which of the following best describes the surface marking of the tricuspid valve:

    >
  • Ciprofloxacin: Pharmacology

    Regarding ciprofloxacin, which of the following statements is CORRECT:

    >
  • Dermatomal Supply of the Upper Limb

    A 43 year old tree surgeon is brought to the ED after falling approximately 10 metres from a tree. During assessment of the C-spine he comp

    >
  • Sickle Cell Disease

    The sickle cell trait has a protective advantage against which of the following infections:

    >
  • Clinical Features of Threadworm Infection

    Regarding threadworms, which of the following statements is CORRECT:

    >
  • Pathogenesis of Tetanus

    A mother brings her child to ED with a dirty wound sustained at a playground. The patient is due a tetanus booster and you decide to give i

    >
  • x

    Blood Groups

    Regarding red blood cell group antigens and antibodies, which of the following statements is CORRECT:

    >
  • Clinical Effects of Hypoglossal Nerve Lesion

    A 28 year old man presents to ED complaining of severe headaches and dizziness. Imaging shows a tumour compressing the hypoglossal canal. Wh

    >
  • Insulin: Mechanism of Action

    Which of the following is NOT an action of insulin:

    >
  • Surface Anatomy of the Abdominal Aorta

    The abdominal aorta begins at which vertebral level:

    >
  • Flumazenil: Indications

    Flumazenil is a reversal agent for which of the following groups of drugs:

    >
  • Vasoconstrictor Sympathomimetics: Mechanism of Action

    What is the main mechanism of action of vasoconstrictor sympathomimetics:

    >
  • Contents of the Popliteal Fossa

    A 67 year old man presents to the ED complaining of pain and swelling to the posterior knee. On examination you note a tender swelling in th

    >
  • Control of Exocrine Pancreas Secretion

    Pancreatic exocrine secretion is increased by which of the following:

    >
  • Local Anaesthetics: Toxicity

    Regarding local anaesthetic toxicity, which of the following statements is INCORRECT:

    >
  • Attachments of the Flexor Retinaculum

    A 29 year old woman is brought to the ED after concerns were raised for her welfare by a neighbour. She has a deep laceration to the anterio

    >
  • x

    Renal Handling of Potassium

    Approximately what percentage of filtered potassium is reabsorbed in the proximal tubule:

    >
  • Haemoglobin

    Regarding haemoglobin, which of the following statements is CORRECT:

    >
  • Control of Gastric Acid Secretion

    Which of the following constitutes the gastric proton pump:

    >
  • Mechanism of Vitamin B12 Absorption

    Regarding vitamin B12 absorption, which of the following statements is CORRECT:

    >
  • x

    Anatomy of the Paranasal Sinuses

    Regarding the paranasal sinuses, which of the following statements is INCORRECT:

    >
  • x

    Function of the Gracilis Muscle

    A 54 year old woman is brought into the ED following a multiple vehicle collision on the nearby motorway. She is haemodynamically stable and

    >
  • x

    Pharmacological Management of Gout

    Regarding the management of gout, which of the following statements is CORRECT:

    >
  • Complications of Gonorrhoea

    A patient presents to ED with a fever and a red, hot swollen painful left knee that is painful to move. On further questioning, you discover

    >
  • x

    Innervation of the Pancreas

    A patient presents to ED with acute pancreatitis. Pain from the pancreas is typically referred to the dermatomes supplied by which of the fo

    >
  • Origin of the Obturator Nerve

    A 43 year old window cleaner is brought to the ED after falling from a 5 metre platform. Imaging has shown multiple vertebral fractures and

    >
  • Mechanism of Action of Diuretics

    At which Na+ transporter do thiazide diuretics primarily act:

    >
  • Measurement of Renal Clearance

    Glomerular filtration rate can be calculated using any substance that:

    >
  • x

    >
  • Pharmacological Management of Gout

    A 34 year old overweight man, who has a history of gout, presents to ED with an acutely exquisitely tender big toe. His big toe is red, hot

    >
  • Movements of the Hip Joint

    A 42 year old man presents to ED following a hip injury. On examination you note weak lateral rotation. Which of the following muscles is mo

    >
  • Classification of Acute Asthma

    Which of the following clinical features would characterise an asthma attack in an adult as severe:

    >
  • x

    Generation of an Action Potential

    Regarding the refractory period, which of the following statements is INCORRECT:

    >
  • Definition of Lung Volumes and Capacities

    Which of the following best describes the tidal volume (TV):

    >
  • Key Anatomical Landmarks in Tracheotomy

    The anaesthetist is attempting to intubate an unconscious patient who is unable to maintain their airway. The anaesthetist finds himself in

    >
  • Control of Gastric Emptying

    Gastric emptying is increased by all of the following EXCEPT for:

    >
  • x

    Typical vs Atypical Ribs

    Which of the following atypical ribs articulates with both its corresponding vertebra and the vertebra above:

    >
  • x

    Anatomical Relations of the Stomach

    The stomach lies anterior to all of the following structures EXCEPT for the:

    >
  • Lymphatic Drainage of the Breast

    A 43 year old woman has presented to the ED in distress. She tells you she has found a new lump in her left breast. She is new to the area a

    >
  • Anatomy of the Olfactory Nerve

    Regarding the olfactory nerve, which of the following statements is CORRECT:

    >
  • Regulation of Aldosterone

    Which of the following hormones is released in direct response to high plasma [K+]:

    >
  • Anatomical Location of the Pituitary Gland

    The pituitary gland sits within a small depression in which of the following skull bones:

    >
  • Attachments of the Subscapularis Muscle

    A 34 year old office worker presents to the Emergency Department complaining of pain in the left shoulder. You perform a full shoulder exami

    >
  • Infectious Diseases caused by Herpesviruses

    Which of the following infectious diseases is NOT caused by a herpesvirus:

    >
  • x

    Clinical Effects of Obturator Nerve Injury

    A 63 year old woman with advanced ovarian malignancy presents to ED complaining of weakness of her left leg while walking. Examination revea

    >
  • Regulation of Calcitonin

    Calcitonin is secreted primarily in response to which of the following:

    >
  • Vancomycin: Indications

    All of the following antibiotics are commonly implicated in causing C. difficile colitis EXCEPT for:

    >
  • Clinical Effects of Ulnar Nerve Injury

    A 32 year old woman sustains an injury to the ulnar nerve at the elbow after sustaining a fracture of the medial epicondyle. Which of the fo

    >
  • Clinical Effects of Median Nerve Injury

    A 21 year old female presents to ED following an attempted suicide attempt. She has a deep laceration to her anterior forearm. Further explo

    >
  • Location of the Brainstem Nuclei

    Which of the following brainstem nuclei is NOT located in the pons:

    >
  • Water vs Fat Soluble Vitamins

    Regarding vitamins, which of the following statements is CORRECT:

    >
  • Doxycycline: Side Effects

    A 19 year old patient presents to ED with pelvic cramps and spotting. A pregnancy test is positive. You note that she is taking doxycycline

    >
  • Definition of Pathogen

    Which of the following best describes a pathogen:

    >
  • Function of Angiotensin II

    Where does angiotensin II directly act on the renal nephron:

    >
  • Management of Tuberculosis

    A patient on treatment for tuberculosis infection presents to ED. The patient was started on the standard treatment regimen for fully suscep

    >
  • Ascending Tracts of the Spinal Cord

    Which of the following spinal tracts conveys nociceptive input from the contralateral side of the body:

    >
  • x

    Function of the Hamstring Muscles

    A 32 year old man presents to the ED after sustaining multiple stab wounds to the right thigh during an altercation in a pub. Imaging has sh

    >
  • x

    Local Anaesthetics: Comparison of Drugs

    Which of the following local anaesthetics is typically used for a Bier's block:

    >
  • Structure of the Ductus Deferens

    The ductus deferens originates from which of the following structures:

    >
  • Production of Gastrin

    Gastrin is secreted by which of the following cell types in the stomach:

    >
  • Production of Glucagon

    Alpha cells of the endocrine pancreas produce which of the following hormones:

    >
  • Infectious Disease caused by Clostridium Botulinum

    A patient presents with a progressive symmetric descending flaccid paralysis following a 2 day history of diarrhoea and vomiting. He initial

    >
  • x

    Macrolides: Mechanism of Action

    What is the mechanism of action of macrolide antibiotics:

    >
  • Components of the Quadriceps Femoris Muscle

    A 27 year old woman has sustained an injury to her quadriceps femoris muscle group after falling through a glass door. Which of the followin

    >
  • Adenosine: Side Effects

    Which of the following is NOT a common side effect of adenosine:

    >
  • Phases of Gastric Secretion

    Regarding the cephalic phase of gastric secretion, which of the following statements is CORRECT:

    >
  • x

    Structure of the Peripheral Vascular System

    Regarding blood vessels, which of the following statements is CORRECT:

    >
  • x

    Disadvantages of Cohort Studies

    Which of the following is NOT a disadvantage of a cohort study used to investigate the relationship between exposure to a risk factor and a

    >
  • x

    Acute Inflammation

    A 21 year old patient presents with a red hot arm which developed following an insect bit. You diagnose acute cellulitis. Which of the follo

    >
  • Microbial Mechanisms of Immune Evasion

    Streptococcus pneumoniae, Haemophilus influenzae and Neisseria meningitidis all colonise the upper respiratory tract and can spread from the

    >
  • Anatomical Relations of the Thyroid Gland

    A 34 year old woman presents to ED complaining of a hoarse voice. She underwent a thyroidectomy 2 weeks ago. Which of the following nerves w

    >
  • Anatomical Course of the Femoral Nerve

    A 34 year old man presents to the ED after sustaining multiple deep stab wounds during an altercation in a pub. Imaging has shown an injury

    >
  • x

    Innervation of the Pleura

    A 64 year old man presents to ED complaining of right sided chest pain that is worse on coughing. Which of the following nerves is most like

    >
  • Function of the Gut Flora

    Regarding the intestinal bacterial flora, which of the following statements is CORRECT:

    >
  • Renal Handling of Phosphate

    All of the following increase renal phosphate excretion EXCEPT for:

    >
  • Action Potential of the Ventricular Myocyte

    In the ventricular myocyte action potential, depolarisation occurs through the opening of:

    >
  • Definition of Lung Volumes and Capacities

    Which of the following describes the volume change of the lung between a maximum inspiration and a maximum expiration:

    >
  • Management of Tetanus-Prone Wounds

    You are leading a teaching session on tetanus prophylaxis. Regarding management of a tetanus-prone wound which of the following statements i

    >
  • x

    Function of Parathyroid Hormone

    How does parathyroid hormone (PTH) affect renal handling of phosphate:

    >
  • Calculation of Sensitivity

    A new test is being developed to diagnose chlamydia. 1000 people aged 15 – 35 years attending a GUM clinic undergo the new test and the cu

    >
  • Clinical Features of Rubella

    Regarding rubella, which of the following statements is INCORRECT:

    >
  • x

    Functional Anatomy of the Small Intestine

    Which of the following does NOT play a role in increasing the surface area of the absorptive surface in the small intestine:

    >
  • Production of Pepsin

    Pepsinogen is activated to pepsin by which of the following:

    >
  • Production of Parathyroid Hormone

    Parathyroid hormone is released by which of the following:

    >
  • x

    Control of Gastric Acid Secretion

    Secretion of hydrochloric acid from parietal cells is stimulated by which of the following:

    >
  • Amoxicillin: Indications

    Amoxicillin is used first line for all of the following infections EXCEPT for:

    >
  • Nerves of the Lumbar Plexus

    The iliohypogastric nerve innervates which of the following muscles:

    >
  • x

    Anatomy of the Hard Palate

    Regarding the hard palate, which of the following statements is CORRECT:

    >
  • x

    ALS Treatment Algorithm

    In adult basic life support, chest compressions should be performed at which of the following rates:

    >
  • Coagulation Cascade

    Regarding the coagulation cascade, the tenase complex in the extrinsic pathway is the:

    >
  • x

    Anatomical Barriers to Infection

    Which of the following is NOT an anatomical barrier to infection:

    >
  • Production of Catecholamines

    Catecholamines are secreted by which of the following:

    >
  • Pharmacological Management of Acute Asthma

    Regarding the management of acute asthma in adults, which of the following statements is INCORRECT:

    >
  • ECG Deflections during the Cardiac Cycle

    Which of the following represents ventricular depolarisation on the ECG:

    >
  • x

    Pharmacological Management of Thiamine Deficiency

    A 64 year old man, with a history of chronic alcohol abuse, presents to ED in alcohol withdrawal as he ran out of beer money. He is unkempt

    >
  • x

    Function of the Gastrocnemius Muscle

    The gastrocnemius muscle acts to produce which of the following movements:

    >
  • Antihistamines: Indications

    Which of the following is NOT an indication for a H1 receptor antihistamine:

    >
  • Microbial Mechanisms of Immune Evasion

    Which of the following microbes has a polysaccharide capsule:

    >
  • Relative Fluid Distribution in Fluid Spaces

    Regarding fluid balance, which of the following statements is CORRECT:

    >
  • Function of Atrial Natriuretic Peptide

    Atrial natriuretic peptide (ANP) has the primary function of which of the following:

    >
  • Function of the Obturator Externus Muscle

    A 19 year old man self presents to the ED following a fight in a nearby street. He has sustained multiple stab wounds and lacerations to the

    >
  • Production and Function of Bile

    Regarding bile, which of the following statements is CORRECT:

    >
  • Immune Response

    Regarding the major histocompatibility complex (MHC) molecules, which of the following statements is CORRECT:

    >
  • Complement Cascade

    C5 - C9 deficiency leads to particular susceptibility of infection with which of the following:

    >
  • Definition of Lung Volumes and Capacities

    Total lung capacity (TLC) is calculated using which of the following:

    >
  • Function of the Tibialis Posterior Muscle

    The tibialis posterior muscle acts to produce which of the following movements:

    >
  • Generation of an Action Potential

    The rising phase of the action potential of a nerve occurs due to which of the following:

    >
  • Movements of the Eyeball

    Depression of the eyeball is primarily produced by which of the following muscles:

    >
  • x

    Anatomy of the Eyeball

    Regarding the eyeball, which of the following statements is INCORRECT:

    >
  • Microstructure of the Cardiac Myocyte

    Which of the following structures prevents a direct electrical pathway from the atria to the ventricles:

    >
  • Muscles of the Anterior Abdominal Wall

    The flat anterior abdominal wall muscles are comprised of which of the following muscles:

    >
  • Movements of the Thoracic Wall

    The 'bucket handle' movement of the thoracic wall describes which of the following movements:

    >
  • Beta-2 Agonists: Mechanism of Action

    Selective beta-2 agonists predominantly have which of the following clinical effects:

    >
  • x

    Control of Gastric Acid Secretion

    Regarding gastric acid secretion, which of the following statements is INCORRECT:

    >
  • Anaemia of Chronic Disease

    A patient is found to be anaemic. Which one of the following blood results would favour a diagnosis of anaemia of chronic disease rather tha

    >
  • Antacid Drugs: Interactions

    A patient presents to ED with heartburn for which they already take regular antacids. Which of the following drugs can be affected if taken

    >
  • ECG Deflections during the Cardiac Cycle

    Which of the following represents atrial depolarisation on the ECG:

    >
  • Warfarin: Mechanism of Action

    What is the mechanism of action of warfarin:

    >
  • Local Control of Blood Flow

    The following are important mediators of metabolic hyperaemia in blood vessels, EXCEPT for:

    >
  • x

    Function of the Renin-Angiotensin-Aldosterone System

    Regarding the renin-angiotensin-aldosterone system (RAAS), which of the following statements is CORRECT:

    >
  • x

    Innervation of the External Nose

    Regarding the external nose, which of the following statements is INCORRECT:

    >
  • Function of the Adrenal Gland

    Regarding the adrenal glands, which of the following statements is CORRECT:

    >
  • Risk Factors for Klebsiella Infection

    Which patient group are most commonly associated with infection with Klebsiella spp:

    >
  • Calculation of Total Blood Volume

    What is the normal total volume of blood in the circulatory system of a healthy adult male:

    >
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