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Questions Answered: 128

Final Score 91%

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  • Renal Handling of Phosphate

    Regarding renal phosphate handling, which of the following statements is CORRECT:

    >
  • Increased vs Normal Anion Gap

    Which of the following is typically a cause of a normal anion gap metabolic acidosis:

    >
  • Autoregulation of Renal Blood Flow

    Which of the following does NOT act to cause vasoconstriction of the glomerular capillaries:

    >
  • Disturbance of Acid-Base Balance

    A patient presents with vomiting and diarrhoea ongoing for 3 days. He is tachycardic and tachypnoeic. Describe the acid-base balance disturb

    >
  • Function of the Distal Collecting System

    Regarding the distal nephron, which of the following statements is CORRECT:

    >
  • x

    Function of Atrial Natriuretic Peptide

    Atrial natriuretic peptide (ANP) acts to cause all of the following effects EXCEPT for:

    >
  • Calculation of the Anion Gap

    A 35 year old man is brought to the emergency department having been found collapsed by his girlfriend. Calculate his anion gap using the bl

    >
  • Renal Handling of Potassium

    Renal potassium excretion is promoted by all but which one of the following:

    >
  • Clinical Effects of Hyperkalaemia

    Which of the following is a clinical effect of hyperkalaemia:

    >
  • Renal Regulation of Acid-Base Balance

    Regarding bicarbonate handling by the proximal tubule, which of the following statements is CORRECT:

    >
  • Structure of the Glomerulus

    Mesangial cells surround the glomerular capillaries and act to perform all EXCEPT which of the following functions:

    >
  • Functional Anatomy of the Kidney

    Regarding the kidneys, which of the following statements is INCORRECT:

    >
  • Production of Renin

    Renin is released in response to all of the following EXCEPT for:

    >
  • Disturbance of Acid-Base Balance

    A 35 year old man is brought to the emergency department having been found collapsed by his girlfriend. What is the most likely diagnosis ta

    >
  • Clinical Effects of Hyperkalaemia

    Which of the following is an ECG change typically associated with hyperkalaemia:

    >
  • Clinical Effects of Hyperkalaemia

    A patient with known renal disease is sent in by his GP with a potassium of 7.5 mEq/L. Which of the following ECG changes might indicate imm

    >
  • Function of the Loop of Henle

    Which part of the loop of Henle is impermeable to water:

    >
  • x

    Regulation of Glomerular Filtration Rate

    In the glomerulus, if the diameter of the afferent arteriole is reduced relative to the diameter of the efferent arteriole:

    >
  • Function of the Juxtaglomerular Apparatus

    What is the role of the juxtaglomerular (granular) cells of the juxtaglomerular apparatus:

    >
  • x

    Disturbance of Acid-Base Balance

    You review a patient in the Emergency Department who is complaining of feeling dizzy and breathless. Which of the following patterns best de

    >
  • Function of the Proximal Tubule

    Where in the nephron is most water reabsorbed:

    >
  • Renal Handling of Sodium

    About what percentage of filtered Na+ is reabsorbed in the proximal tubule:

    >
  • Function of Angiotensin II

    Where does angiotensin II directly act on the renal nephron:

    >
  • Function of the Renin-Angiotensin-Aldosterone System

    Which of the following causes increased aldosterone secretion:

    >
  • Blood Supply to the Kidneys

    Regarding blood supply to the kidneys, which of the following statements is CORRECT:

    >
  • Autoregulation of Renal Blood Flow

    In tubuloglomerular feedback, where is increased tubular flow rate detected in the nephron:

    >
  • Renal Production of Hormones

    The kidneys produce all of the following hormones EXCEPT for:

    >
  • Measurement of Renal Clearance

    Glomerular filtration rate can be calculated using any substance that:

    >
  • Renal Handling of Potassium

    How is filtered K+ mainly reabsorbed in the thick ascending limb of the loop of Henle:

    >
  • Measurement of Renal Clearance

    Regarding renal clearance, which of the following statements is CORRECT:

    >
  • Function of the Loop Of Henle

    Regarding the loop of Henle, which of the following statements is CORRECT:

    >
  • Transport Maximum of Glucose

    What is the approximate renal threshold for glucose:

    >
  • Increased vs Normal Anion Gap

    Which of the following is typically a cause of an increased anion gap metabolic acidosis:

    >
  • Function of the Juxtaglomerular Apparatus

    What is the role of the macula densa cells of the juxtaglomerular apparatus:

    >
  • Autoregulation of Renal Blood Flow

    Regarding regulation of renal blood flow, which of the following statements is CORRECT:

    >
  • Calculation of the Anion Gap

    Which of the following cations are required to calculate the anion gap:

    >
  • Function of the Proximal Tubule

    Regarding Na+ reabsorption in the proximal tubule, which of the following statements is INCORRECT:

    >
  • x

    Renal Production of Hormones

    Which of the following is synthesised by the kidney:

    >
  • Normal Values for Arterial Blood Gases

    What is the normal range for arterial PaCO2:

    >
  • Renal Handling of Calcium

    Regarding calcium handling by the kidneys, which of the following statements is CORRECT:

    >
  • Autoregulation of Renal Blood Flow

    Regarding renal autoregulation, which of the following typically causes vasoconstriction:

    >
  • Normal Values for Arterial Blood Gases

    What is the normal range of arterial [HCO3-]:

    >
  • Structure of the Juxtaglomerular Apparatus

    The macula densa is located at which of the following sites:

    >
  • Increased vs Normal Anion Gap

    Which of the following is typically a cause of a normal anion gap metabolic acidosis:

    >
  • x

    Production of Renin

    Renin is produced at which of the following sites in the kidney:

    >
  • Renal Handling of Calcium

    Regarding calcium, which of the following statements is CORRECT:

    >
  • Renal Handling of Sodium

    Regarding Na+ handling in the kidney, which of the following statements is CORRECT:

    >
  • Functional Anatomy of the Nephron

    The renal corpuscle, consisting of the Bowman's capsule and the glomerulus is found where in the kidney:

    >
  • Disturbance of Acid-Base Balance

    You review a patient in ED who has taken an aspirin overdose. Which of the following patterns best describes the following arterial blood ga

    >
  • Calculation of the Anion Gap

    You are calculating the anion gap on a patient with an acid-base disturbance and you find the anion gap to be low. Which of the following is

    >
  • Renal Regulation of Acid-Base Balance

    The following are all important buffers of H+ EXCEPT for:

    >
  • Renal Regulation of Acid-Base Balance

    Approximately what percentage of filtered bicarbonate is reabsorbed in the proximal tubule:

    >
  • Function of the Juxtaglomerular Apparatus

    The macula densa predominantly detects which of the following:

    >
  • Function of the Loop of Henle

    In which part of the loop of Henle is Na+ reabsorbed via the Na+/K+/2Cl- symporter:

    >
  • Renal Handling of Urea

    Regarding renal handling of urea, which of the following statements is CORRECT:

    >
  • x

    Structure of the Glomerular Filtration Barrier

    Which of the following does NOT contribute to the glomerular filtration barrier:

    >
  • Clinical Effects of Hyperkalaemia

    Which of the following is NOT an ECG change typically associated with hyperkalaemia:

    >
  • Function of Atrial Natriuretic Peptide

    Atrial natriuretic peptide (ANP) has the primary function of which of the following:

    >
  • Function of the Proximal Tubule

    Where is most water reabsorbed in the nephron:

    >
  • Disturbance of Acid-Base Balance

    Which of the following conditions is most likely to cause the following blood gas result (on air): pH = 7.34 PaO2 = 9 kPa PaCO2 =

    >
  • Renal Handling of Phosphate

    Regarding phosphate, which of the following statements is CORRECT:

    >
  • Renal Handling of Sodium

    About what percentage of filtered Na+ is reabsorbed in the loop of Henle:

    >
  • x

    Renal Handling of Phosphate

    Regarding renal phosphate handling, which of the following statements is CORRECT:

    >
  • Function of the Proximal Tubule

    Regarding reabsorption in the proximal tubule, which of the following statements is INCORRECT:

    >
  • Calculation of the Anion Gap

    You are calculating the anion gap of an unconscious patient with a metabolic acidosis. Which of the following anions are required to calcula

    >
  • Autoregulation of Renal Blood Flow

    Which of the following does NOT act to cause vasodilation of the glomerular capillaries:

    >
  • Renal Handling of Potassium

    Approximately what percentage of filtered potassium is reabsorbed in the proximal tubule:

    >
  • Increased vs Normal Anion Gap

    Which of the following is typically a cause of a normal anion gap metabolic acidosis:

    >
  • Function of the Renin-Angiotensin-Aldosterone System

    Which of the following is a response to increased sympathetic innervation to the kidney following a fall in extracellular volume:

    >
  • Function of the Loop Of Henle

    Regarding the loop of Henle, which of the following statements is CORRECT:

    >
  • Disturbance of Acid-Base Balance

    What pattern of acid-base disturbance is shown by the blood gas results (on normal air) below: pH = 7.37 PaO2 9 kPa PaCO2 = 7.5 k

    >
  • Production of Angiotensin II

    Where is angiotensin I primarily converted to angiotensin II:

    >
  • Renal Handling Of Urea

    Regarding renal handling of urea, which of the following statements is CORRECT:

    >
  • Function of the Proximal Tubule

    How is most Na+ reabsorbed from the lumen of the proximal tubule:

    >
  • Production of Atrial Natriuretic Peptide

    Atrial natriuretic peptide (ANP) is primarily produced in response to:

    >
  • Renal Handling of Sodium

    Which of the following hormones acts to inhibit Na+ reabsorption in the distal nephron:

    >
  • Production of Atrial Natriuretic Peptide

    Atrial natriuretic peptide (ANP) is primarily produced by which of the following:

    >
  • Renal Handling of Calcium

    Regarding calcium, which of the following statements is CORRECT:

    >
  • Structure of the Glomerular Filtration Barrier

    Regarding the glomerular filtration barrier, which of the following statements is CORRECT:

    >
  • Clinical Effects of Hypokalaemia

    A 29 year old man presents to the Emergency Department complaining of fatigue and muscle cramps. He is found to be hypokalaemic. A 12-lead E

    >
  • Renal Handling of Phosphate

    All of the following increase renal phosphate excretion EXCEPT for:

    >
  • Renal Handling of Calcium

    Regarding calcium handling by the kidneys, which of the following statements is CORRECT:

    >
  • Transport Maximum of Glucose

    Regarding glucose handling by the kidneys, which of the following statements is CORRECT:

    >
  • Functional Anatomy of the Nephron

    Regarding the nephrons, which of the following statements is INCORRECT:

    >
  • x

    Mechanism of Action of Diuretics

    Regarding diuretics, which of the following statements is CORRECT:

    >
  • Measurement of Glomerular Filtration Rate

    The normal glomerular filtration rate (GFR) in a healthy adult is about _______ :

    >
  • Renal Handling of Potassium

    Where in the nephron is most K+ reabsorbed:

    >
  • Production of Renin

    Renin is produced by which of the following:

    >
  • Disturbance of Acid-Base Balance

    What type of breathing pattern is classically seen in metabolic acidosis:

    >
  • Increased vs Normal Anion Gap

    Which of the following is typically a cause of an increased anion gap metabolic acidosis:

    >
  • Autoregulation of Renal Blood Flow

    Regarding renal autoregulation, which of the following does NOT cause vasoconstriction:

    >
  • Blood Supply to the Kidney

    The kidneys receive around ______% of total cardiac output:

    >
  • Mechanism of Action of Diuretics

    At which Na+ transporter do thiazide diuretics primarily act:

    >
  • Production of Renin

    Which of the following is produced in the kidney:

    >
  • Clinical Effects of Hypokalaemia

    Which of the following is NOT a clinical feature of hypokalaemia:

    >
  • Structure of the Glomerular Filtration Barrier

    Regarding the glomerular filtration barrier, which of the following statements is CORRECT:

    >
  • x

    Renal Handling of Potassium

    Renal regulation of potassium is primarily controlled by which of the following hormones:

    >
  • Disturbance of Acid-Base Balance

    A 35 year old woman who is 9 weeks pregnant presents to ED with severe persistent morning sickness. What acid-base disturbance would you mos

    >
  • Function of the Glomerular Filtration Barrier

    Molecules with a molecular weight of less than which of the following are filtered freely at the glomerular filtration barrier:

    >
  • Measurement of Renal Plasma Flow

    The normal renal plasma flow in a healthy adult is about ________ :

    >
  • Mechanism of Action of Diuretics

    Where in the nephron do loop diuretics primarily act:

    >
  • Function of the Proximal Tubule

    Where in the nephron is most Na+ reabsorbed:

    >
  • Production of Renin

    Where is renin produced:

    >
  • Increased vs Normal Anion Gap

    Which of the following is typically a cause of an increased anion gap metabolic acidosis:

    >
  • Function of the Loop of Henle

    Which of the following vessels is involved with countercurrent multiplication in the renal medulla:

    >
  • Function of the Renin-Angiotensin-Aldosterone System

    Regarding the renin-angiotensin-aldosterone system (RAAS), which of the following statements is CORRECT:

    >
  • Renal Handling of Potassium

    Regarding renal potassium handling, which of the following statements is INCORRECT:

    >
  • Mechanism of Action of Diuretics

    At which Na+ transporter do loop diuretics primarily act:

    >
  • Function of the Proximal Tubule

    Regarding the proximal tubule, which of the following statements is CORRECT:

    >
  • Renal Handling of Sodium

    Which of the following hormones' primary action is to enhance Na+ reabsorption in the distal nephron:

    >
  • Function of Angiotensin II

    Angiotensin II acts to cause all but which one of the following effects:

    >
  • Function of the Distal Collecting System

    Regarding the distal nephron, which of the following statements is CORRECT:

    >
  • Calculation of the Filtration Fraction

    The normal glomerular filtration fraction in a healthy adult is about ______ %:

    >
  • Normal Values for Arterial Blood Gases

    What is the normal range of arterial pH:

    >
  • Renal Handling of Urea

    Regarding renal handling of urea, which of the following statements is INCORRECT:

    >
  • x

    Function of the Proximal Tubule

    About what percentage of filtered water is reabsorbed in the proximal tubule:

    >
  • Function of the Proximal Tubule

    The proximal tubule is the primary site of reabsorption in the nephron for which of the following:

    >
  • Mechanism of Action of Diuretics

    Where in the nephron do thiazide diuretics primarily act:

    >
  • Renal Regulation of Acid-Base Balance

    Regarding acid-base regulation in the kidneys, which of the following statements is CORRECT:

    >
  • Renal Handling of Calcium

    Which of the following does NOT increase free ionised calcium levels:

    >
  • Clinical Effects of Hypokalaemia

    Which of the following is NOT an ECG change typically associated with hypokalaemia:

    >
  • Production of Angiotensinogen

    Where is angiotensinogen produced:

    >
  • Interpretation of Base Excess

    A high (positive) base excess is typically seen in which of the following:

    >
  • Function of the Loop of Henle

    In which part of the loop of Henle is water reabsorbed:

    >
  • Clinical Effects of Hyperkalaemia

    A patient is sent into ED by his GP with an abnormal blood test result. His ECG performed at triage is shown below. What is the likely abnor

    >
  • Renal Handling of Sodium

    Which of the following hormones regulates Na+ reabsorption in the proximal tubule:

    >
  • Function of the Loop Of Henle

    Regarding the loop of Henle, which of the following statements is CORRECT:

    >
  • x

    Regulation of Glomerular Filtration Rate

    In the glomerulus, if the diameter of the efferent arteriole is decreased relative to the diameter of the afferent arteriole:

    >
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